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This product should be used only as directed on the label. It should not be used if you are pregnant or nursing.

Consult with a physician before use if you have a serious medical condition or use prescription medications. All trademarks and copyrights are property of their respective owners and are not affiliated with nor do they endorse this product.

CBD For Acne. CBD For Addiction. CBD For Anorexia. CBD For Anxiety. CBD For Arthritis. CBD For Asthma. CBD For Autism. CBD For Cancer. This can be increased at weekly intervals if necessary, up to a maximum of There is no strong scientific evidence that nonprescription cannabidiol products are beneficial for epilepsy.

Other names. Clin Pharmacokinet. View abstract. Abrupt withdrawal of cannabidiol CBD : A randomized trial.

Epilepsy Behav. Clin Toxicol Phila. Clin Pharmacol Drug Dev. JAMA Neurol. Cannabidiol efficacy and clobazam status: A systematic review and meta-analysis.

Evaluation of pharmacokinetics and acute anti-inflammatory potential of two oral cannabidiol preparations in healthy adults. Phytother Res.

Pediatr Neurol. Efficacy and adverse event profile of cannabidiol and medicinal cannabis for treatment-resistant epilepsy: Systematic review and meta-analysis.

The effect of cannabidiol on the pharmacokinetics of carbamazepine in rats. Naunyn Schmiedebergs Arch Pharmacol. A phase 1, randomized, pharmacokinetic trial of the effect of different meal compositions, whole milk, and alcohol on cannabidiol exposure and safety in healthy subjects.

Adverse effects of cannabidiol: a systematic review and meta-analysis of randomized clinical trials.

CNS Drugs. Bass J, Linz DR. Cannabidiol and - Delta9-tetrahydrocannabinol are neuroprotective antioxidants.

Probing the antioxidant activity of [delta]-tetrahydrocannabinol and cannabidiol in Cannabis sativa extracts. Hazekamp A. The trouble with CBD oil.

Med Cannabis Cannabinoids. Curr Pharm Biotechnol. Effects of acute cannabidiol administration on anxiety and tremors induced by a Simulated Public Speaking Test in patients with Parkinson's disease.

J Psychopharmacol. J Clin Med. Masataka N. Front Psychol. Effects of short-term cannabidiol treatment on response to social stress in subjects at clinical high risk of developing psychosis.

Psychopharmacology Berl. Synthetic pharmaceutical grade cannabidiol for treatment of refractory infantile spasms: A multicenter phase-2 study.

Front Neurol. Subsidiary Greenwich Biosciences, Inc. Press release. October J Clin Pharmacol. Higher cannabidiol plasma levels are associated with better seizure response following treatment with a pharmaceutical grade cannabidiol.

The effect of cannabidiol CBD on low-frequency activity and functional connectivity in the brain of adults with and without autism spectrum disorder ASD.

Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder.

Adv Ther. Cognitive functioning following long-term cannabidiol use in adults with treatment-resistant epilepsy. Evidence of a clinically significant drug-drug interaction between cannabidiol and tacrolimus.

Am J Transplant. Long-term safety and efficacy of cannabidiol in children and adults with treatment resistant Lennox-Gastaut syndrome or Dravet syndrome: Expanded access program results.

Epilepsy Res. Effects of cannabidiol on brivaracetam plasma levels. J Neurodev Disord. Inflamm Bowel Dis. Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy.

Cannabidiol CBD content in vaporized cannabis does not prevent tetrahydrocannabinol THC -induced impairment of driving and cognition.

Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions. Product information for Marinol.

North Chicago, IL August Epidiolex cannabidiol prescribing information. Greenwich Biosciences, Inc. Food and Drug Administration Web site.

Accessed May 7, Agriculture Improvement Act, S. Drug Enforcement Administration, Department of Justice.

Final order. Fed Regist. Abuse potential assessment of cannabidiol CBD in recreational polydrug users: A randomized, double-blind, controlled trial.

Epub Oct 2. Epub Jul Cannabidiol improves frequency and severity of seizures and reduces adverse events in an open-label add-on prospective study.

Epub Aug 9. Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Braz J Psychiatry.

Epub Oct The unexpected identification of the cannabimimetic, 5F-ADB, and dextromethorphan in commercially available cannabidiol e-liquids. Forensic Sci Int.

Epub Nov 1. Am J Psychiatry. N Engl J Med. J Nutr. Low-dose cannabidiol is safe but not effective in the treatment of Crohn's Disease, a randomized controlled trial.

Dig Dis Sci. Cannabidiol treatment for refractory seizures in Sturge-Weber Syndrome. Cannabidiol for the prevention of graft-versus-host-disease after allogeneic hematopoietic cell transplantation: results of a phase II study.

Biol Blood Marrow Transplant. Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy.

Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial. Lancet Neurol. Efficacy and safety of cannabidiol and tetrahydrocannabivarin on glycemic and lipid parameters in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, parallel group pilot study.

Diabetes Care. Cannabidiol as a potential treatment for febrile infection-related epilepsy syndrome FIRES in the acute and chronic phases.

J Child Neurol. Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex. Interactions between cannabidiol and commonly used antiepileptic drugs.

Trial of cannabidiol for drug-resistant seizures in the Dravet Syndrome. Labeling accuracy of cannabidiol extracts sold online.

JAMA Nov; The non-psychoactive cannabis-constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.

Analgesic and anti-inflammatory activity of constituents of Cannabis sativa L. Inflammation ; Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania.

J Psychopharmacol ; Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression. Br J Pharmacol ; Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kappaB involvement.

Neurosci Lett ; Cannabidiol: a promising new drug for neurodegenerative disorders? CNS Neurosci Ther ; Bisogno T, Di Marzo Y. The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses.

Curr Pharm Des ; Zuardi AW. Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action. Rev Bras Psiquiatr ; Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.

Trends Pharmacol Sci ; Booz GW. Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress.

Free Radic Biol Med ; Pickens JT. Sedative activity of cannabis in relation to its delta'-trans-tetrahydrocannabinol and cannabidiol content.

Monti JM. Hypnoticlike effects of cannabidiol in the rat. Psychopharmacology Berl ; Karler R, Turkanis SA. Subacute cannabinoid treatment: anticonvulsant activity and withdrawal excitability in mice.

The anticonvulsant activity of cannabidiol and cannabinol. Life Sci ; Anticonvulsant interaction of cannabidiol and ethosuximide in rats.

J Pharm Pharmacol ; Consroe P, Wolkin A. Cannabidiol-antiepilpetic drug comparisons and interactions in experimentally induced seizures in rats.

J Pharmacol Exp Ther ; Letter: Cannabidiol and Cannabis sativa extract protect mice and rats against convulsive agents. Assessing antidepressant activity in rodents: recent developments and future needs.

Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. Pharmacol Biochem Behav ; Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress.

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. FEBS Lett ; Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.

PLoS One ;6:e Modulation of mediotemporal and ventrostriatal function in humans by Delta9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis.

Arch Gen Psychiatry ; Influence of cannabidiol on deltatetrahydrocannabinol effects. Clin Pharmacol Ther ; Cannabidiol increases Fos expression in the nucleus accumbens but not in the dorsal striatum.

Cannabidiol inhibits the hyperlocomotion induced by psychomimetic drugs in mice. Eur J Pharmacol ; Int J Neuropsychopharmacol ; Effects of cannabidiol in animal models predictive of antipsychotic activity.

Cannabidiol reverses the reduction in social interaction produced by low dose Delta-tetrahydrocannabinol in rats. Cannabidiol as a potential treatment for psychosis.

Eur Neuropsychopharmacol ; Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders.

Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol. Cannabidiol inhibitory effect on marble-burying behavior: involvement of CB1 receptors.

Behav Pharmacol ; Anti-aversive effects of cannabidiol on innate fear-induced behaviors evoked by an ethological model of panic attacks based on a prey vs the wild snake Epicrates cenchria crassus confrontation paradigm.

Neuropsychopharmacology ; NHPs and VHPs may only contain parts of the cannabis and hemp plants that are not considered cannabis under the Cannabis Act or that are excluded from the application of the Act.

This includes things such as:. Edible cannabis will not be permitted for sale until the Regulations Amending the Cannabis Regulations New Classes of Cannabis come into force on October 17, These regulations set out strict controls to reduce the:.

You will not receive a reply. Skip to main content Skip to "About government". Cannabidiol CBD. CBD can be found in different varieties of the cannabis plant, including hemp.

Before the Cannabis Act came into force, CBD was: regulated under the Controlled Drugs and Substances Act strictly controlled It was not legal to produce, sell, import or export CBD unless authorized for medical or scientific purposes.

The Act and accompanying regulations place strict controls on cannabis: possession production distribution sale Health Canada oversees the production of cannabis products.

Health Canada is also responsible for overseeing the distribution and sale of: cannabis, including any CBD-containing cannabis products for medical purposes The provinces and territories are responsible for determining how cannabis is distributed and sold within their jurisdictions.

They set rules around: how cannabis products can be sold where stores may be located how stores must be operated Growing cannabis plants containing CBD for commercial sale To cultivate any cannabis plants that you intend to sell, you must have a federal licence issued under the Cannabis Act.

This licence could be: a cultivation licence under the Cannabis Regulations authorizing growing of cannabis plants with varying amounts of THC and CBD an industrial hemp licence under the Industrial Hemp Regulations authorizing cultivation of specific varieties of cannabis plants with a THC content of no more than 0.

CBD and products containing CBD, such as cannabis oil, may only be sold by a: provincially or territorially-authorized cannabis retailer federally-licensed seller of cannabis for medical purposes Importing and exporting CBD products Movement of cannabis and cannabis products between countries is covered by 3 United Nations drug conventions, including the Single Convention on Narcotic Drugs of as amended by the Protocol.

Any import or export must meet all of these criteria and may only be done: by a holder of a licence issued under the Cannabis Regulation s under an import or export permit issued to the licence holder by Health Canada for that shipment for a legitimate scientific or medical purpose, as per international agreements Industrial hemp Industrial hemp is cannabis that contains 0.

What industrial hemp licence holders may and may not do An industrial hemp licence holder may cultivate hemp to produce a number of different products.

They may: sell viable seeds sell grain i. Importing and exporting industrial hemp The Industrial Hemp Regulations authorize importing and exporting industrial hemp seed or grain, but not the flowering heads, branches or leaves.

The flowering heads, branches and leaves may only be imported or exported by a licence holder under the Cannabis Regulations : with a permit issued under those regulations for legitimate medical and scientific purposes To import or export the industrial hemp seeds or grain, you must: hold a licence from Health Canada have an import or export permit issued by Health Canada When importing or exporting industrial hemp seeds or grain, you may also need to obtain an import or export permit from the other country, depending on their rules.

Hemp-seed oil is marketed in Canada in: food cosmetics natural health products veterinary health products CBD and prescription drugs All phytocannabinoids, with several exceptions, are listed on the Prescription Drug List.

CBD in natural health products, veterinary health products and cosmetics Only limited parts of cannabis or hemp plants may be used in a: natural health product NHPs under the Natural Health Product Regulations veterinary health product VHPs under the Food and Drug Regulations NHPs and VHPs may only contain parts of the cannabis and hemp plants that are not considered cannabis under the Cannabis Act or that are excluded from the application of the Act.

This includes things such as: non-viable seeds hemp-seed derivatives that are compliant with the Industrial Hemp Regulations mature stalks that do not include any leaves, flowers, seeds or branches and fibre from such stalks are also excluded from the Cannabis Act , but they may not be used in veterinary health products.

Deliberately adding phytocannabinoids to such products is not permitted. These same restrictions also apply to cosmetics, which may only contain hemp derivatives.

These regulations set out strict controls to reduce the: appeal of such products to youth; risk of accidental consumption, especially of edible cannabis, including by youth; risk of overconsumption associated with edible cannabis because of the delay in experiencing the effects of cannabis when it is ingested rather than inhaled; and risk of foodborne illness associated with the production and consumption of edible cannabis.

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However in the modern context, it was not until its introduction to American pharmacies by William Brooke O'Shaughnessy in that Cannabis extracts came into mainstream awareness as a medicine.

A wide range of cannabis extracts became easily available and could be gotten from travelling doctors and salesmen, doctors, and drugstores throughout America.

This ended the introduction of the Pure Food and Drug Act. Similar products were also available across Europe. In the early decades of the 21st century, CBD is again becoming well-known for its qualities as a remedy for health problems.

There is some experience that CBD has a positive effect in managing and treating chronic pain, PTSD , anxiety , anxiety disorder , depression , diabetes type 1 , diabetes type 2 , seizures , and also combined with allopathic approaches to diseases including chemotherapy and radiation therapy for treating cancer.

No toxic dose for CBD is known, and there is no record from any source of a death or serious injury from CBD as of this writing.

CBD may be useful either as as treatment for a specific illness or in a smaller dose for maintenance of good health.

Usually, CBD is taken by mouth as oil drops or a powder that dissolves in water, or made into a food to be eaten. Another form of CBD is used on the skin as the oil or a cream to rub in.

CBD is popularly taken in the ' vape ' method from the word "vapor" , with the CBD is heated so it can be inhaled. This method is favoured because the effect is felt sooner than by other means.

Patients who need long-lasting relief from pain or other symptoms such as nausea, may combine two methods: for example, first vape and then eat a food made with CBD.

According to Doctor Grinspoon doctor and professor at Harvard University cannabidiol has 3 uses: leisure, health and pharmacology.

However, where CBD is produced for pharmaceutical purposes as an extract of cannabis, cannabis extracts and tinctures are included in the UN Single Convention on Narcotic Drugs.

A fuller review of extracts or preparations containing almost exclusively CBD will take place in June , when the WHO expert committee will undertake a comprehensive review of cannabis and cannabis related substances.

Not scheduling a substance means that it is not subject to strict international controls, including for production and supply. Its legal status in countries is something for national legislators to decide.

Some countries have eased regulations around cannabidiol, to consider products containing CBD to be medical products.

Cannabidiol and - Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Probing the antioxidant activity of [delta]-tetrahydrocannabinol and cannabidiol in Cannabis sativa extracts.

Hazekamp A. The trouble with CBD oil. Med Cannabis Cannabinoids. Curr Pharm Biotechnol. Effects of acute cannabidiol administration on anxiety and tremors induced by a Simulated Public Speaking Test in patients with Parkinson's disease.

J Psychopharmacol. J Clin Med. Masataka N. Front Psychol. Effects of short-term cannabidiol treatment on response to social stress in subjects at clinical high risk of developing psychosis.

Psychopharmacology Berl. Synthetic pharmaceutical grade cannabidiol for treatment of refractory infantile spasms: A multicenter phase-2 study.

Front Neurol. Subsidiary Greenwich Biosciences, Inc. Press release. October J Clin Pharmacol. Higher cannabidiol plasma levels are associated with better seizure response following treatment with a pharmaceutical grade cannabidiol.

The effect of cannabidiol CBD on low-frequency activity and functional connectivity in the brain of adults with and without autism spectrum disorder ASD.

Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder.

Adv Ther. Cognitive functioning following long-term cannabidiol use in adults with treatment-resistant epilepsy.

Evidence of a clinically significant drug-drug interaction between cannabidiol and tacrolimus. Am J Transplant. Long-term safety and efficacy of cannabidiol in children and adults with treatment resistant Lennox-Gastaut syndrome or Dravet syndrome: Expanded access program results.

Epilepsy Res. Effects of cannabidiol on brivaracetam plasma levels. J Neurodev Disord. Inflamm Bowel Dis. Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy.

Cannabidiol CBD content in vaporized cannabis does not prevent tetrahydrocannabinol THC -induced impairment of driving and cognition.

Coadministered cannabidiol and clobazam: Preclinical evidence for both pharmacodynamic and pharmacokinetic interactions. Product information for Marinol.

North Chicago, IL August Epidiolex cannabidiol prescribing information. Greenwich Biosciences, Inc. Food and Drug Administration Web site.

Accessed May 7, Agriculture Improvement Act, S. Drug Enforcement Administration, Department of Justice. Final order. Fed Regist. Abuse potential assessment of cannabidiol CBD in recreational polydrug users: A randomized, double-blind, controlled trial.

Epub Oct 2. Epub Jul Cannabidiol improves frequency and severity of seizures and reduces adverse events in an open-label add-on prospective study.

Epub Aug 9. Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Braz J Psychiatry.

Epub Oct The unexpected identification of the cannabimimetic, 5F-ADB, and dextromethorphan in commercially available cannabidiol e-liquids.

Forensic Sci Int. Epub Nov 1. Am J Psychiatry. N Engl J Med. J Nutr. Low-dose cannabidiol is safe but not effective in the treatment of Crohn's Disease, a randomized controlled trial.

Dig Dis Sci. Cannabidiol treatment for refractory seizures in Sturge-Weber Syndrome. Cannabidiol for the prevention of graft-versus-host-disease after allogeneic hematopoietic cell transplantation: results of a phase II study.

Biol Blood Marrow Transplant. Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy. Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial.

Lancet Neurol. Efficacy and safety of cannabidiol and tetrahydrocannabivarin on glycemic and lipid parameters in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, parallel group pilot study.

Diabetes Care. Cannabidiol as a potential treatment for febrile infection-related epilepsy syndrome FIRES in the acute and chronic phases.

J Child Neurol. Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex. Interactions between cannabidiol and commonly used antiepileptic drugs.

Trial of cannabidiol for drug-resistant seizures in the Dravet Syndrome. Labeling accuracy of cannabidiol extracts sold online.

JAMA Nov; The non-psychoactive cannabis-constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.

Analgesic and anti-inflammatory activity of constituents of Cannabis sativa L. Inflammation ; Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania.

J Psychopharmacol ; Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression. Br J Pharmacol ; Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kappaB involvement.

Neurosci Lett ; Cannabidiol: a promising new drug for neurodegenerative disorders? CNS Neurosci Ther ; Bisogno T, Di Marzo Y. The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses.

Curr Pharm Des ; Zuardi AW. Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action.

Rev Bras Psiquiatr ; Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb. Trends Pharmacol Sci ; Booz GW.

Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. Free Radic Biol Med ; Pickens JT.

Sedative activity of cannabis in relation to its delta'-trans-tetrahydrocannabinol and cannabidiol content. Monti JM. Hypnoticlike effects of cannabidiol in the rat.

Psychopharmacology Berl ; Karler R, Turkanis SA. Subacute cannabinoid treatment: anticonvulsant activity and withdrawal excitability in mice.

The anticonvulsant activity of cannabidiol and cannabinol. Life Sci ; Anticonvulsant interaction of cannabidiol and ethosuximide in rats.

J Pharm Pharmacol ; Consroe P, Wolkin A. Cannabidiol-antiepilpetic drug comparisons and interactions in experimentally induced seizures in rats.

J Pharmacol Exp Ther ; Letter: Cannabidiol and Cannabis sativa extract protect mice and rats against convulsive agents. Assessing antidepressant activity in rodents: recent developments and future needs.

Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L. Pharmacol Biochem Behav ; Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress.

Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. FEBS Lett ; Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis.

PLoS One ;6:e Modulation of mediotemporal and ventrostriatal function in humans by Delta9-tetrahydrocannabinol: a neural basis for the effects of Cannabis sativa on learning and psychosis.

Arch Gen Psychiatry ; Influence of cannabidiol on deltatetrahydrocannabinol effects. Clin Pharmacol Ther ; Cannabidiol increases Fos expression in the nucleus accumbens but not in the dorsal striatum.

Cannabidiol inhibits the hyperlocomotion induced by psychomimetic drugs in mice. Eur J Pharmacol ; Int J Neuropsychopharmacol ; Effects of cannabidiol in animal models predictive of antipsychotic activity.

Cannabidiol reverses the reduction in social interaction produced by low dose Delta-tetrahydrocannabinol in rats. Cannabidiol as a potential treatment for psychosis.

Eur Neuropsychopharmacol ; Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders.

Modulation of effective connectivity during emotional processing by Delta 9-tetrahydrocannabinol and cannabidiol. Cannabidiol inhibitory effect on marble-burying behavior: involvement of CB1 receptors.

Behav Pharmacol ; Anti-aversive effects of cannabidiol on innate fear-induced behaviors evoked by an ethological model of panic attacks based on a prey vs the wild snake Epicrates cenchria crassus confrontation paradigm.

Neuropsychopharmacology ; Behav Pharmacol ;S Effects of cannabidiol and diazepam on behavioral and cardiovascular responses induced by contextual conditioned fear in rats.

Behav Brain Res ; Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test. Prog Neuropsychopharmacol Biol Psychiatry ; Pharmacological characterization of cannabinoids in the elevated plus maze.

Antianxiety effect of cannabidiol in the elevated plus-maze. Cannabidiol ameliorates cognitive and motor impairments in mice with bile duct ligation.

J Hepatol ; Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.

J Am Coll Cardiol ; Cannabidiol protects retinal neurons by preserving glutamine synthetase activity in diabetes. Mol Vis ; Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes.

Am J Pathol ; Cannabidiol attenuates high glucose-induces endothelial cell inflammatory response and barrier disruption. Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type 1 diabetic peripheral neuropathic pain.

Mol Pain ; Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer. J Mol Med Berl ; A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells.

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